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Gad Rennert, M.D., Ph.D.
Chairman, Dept. Community Medicine and Epidemiology, Carmel Medical Center and Technion Faculty of Medicine, and Director, CHS National Israeli Cancer Control Center
Phone: 972-4-825-0474
Fax: 972-4-834-4358
E-mail: rennert@clalit.org.il
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Education
| INSTITUTION AND LOCATION |
DEGREE |
YEARS |
FIELD OF STUDY |
| University of the Negev, Beer-Sheba, Israel |
MD |
1978-84 |
Medicine |
| School of Public Health, UNC, Chapel Hill |
PhD |
1986-88 |
Public Health/Epidemiology |
A. Current positions and appointments
1990 - Head, Dept. of Epidemiology and Disease Prevention, CHS Headquarters, Tel Aviv,
1992 - Chairman, Department of Community Medicine and Epidemiology, Clalit Health Services, Carmel Medical Center and B. Rappaport Faculty of Medicine, Technion, Haifa, Israel.
1992 - Director, Clalit Health Services National Israeli Cancer Control Center
1992 - Director, The National Israeli Breast Cancer Screening Program. Israel Ministry of Health
1992 - Israeli delegate, Europe Against Cancer, Commission of the European
Communities, Breast Cancer Screening. (EBCN)
1993- Member, National Israeli Oncology Council, Ministry of Health.
1993- International Breast Cancer Screening Network (IBSN) (NCI coordinated).
1993 - Member, Ministry of Health - Head Scientist Committee on Epidemiology.
1994 - Member, Strategic Planning Committee, National Center for Health Policy.
1994 - Member, Managing Board, Israel Cancer Association.
1999 - Member, Ministry of Health - Head Scientist Committee on Research on Cancer.
1998 - Council member, European Association for Cancer Research.
1998 - Member, Planning Committees of National Colorectal Cancer Detection Program.
2000 - Member, Joint Sub-Committee on Onco-genetics, National Oncology Council and Gynecology, Obstetrics and Genetics Council, Ministry of Health.
2000 - Member, Research Committee, National Women's Health Council, Ministry of Health.
2000 - Member, Committee on Preventive Medicine in the Community. The Israel National Institute for Health Policy and Health Services Research. Chairman and program director for workshop on closing the gap between preventive medicine and clinical medicine.
2001 - Advisor on cancer epidemiology and cancer control, Israel Cancer Association
2001 - Chair, Inter-Ministerial Committee on Carcinogens and Mutagens, Ministries of Health, Environmental Protection, Commerce and Industry, Agriculture and Labor and Welfare.
2003 - Member, CHS Strategic Team on Quality Management, Preventive Medicine and Medical Research.
2003 - Board member, International Society of Cancer Chemoprevention.
2003 - Member, Israel Center for Disease Control committee on exceptional morbidity.
2004 - Member, International Colorectal Cancer Screening Network (ICRCSN) (joint USA-CDC, Cancer Research UK, American Cancer Society coordination).
2005 - Director, National Israeli Colon Cancer Program. Israeli Ministry of Health
2007 - Member, European Society for Medical Oncology (ESMO) Faculty list, Cancer Prevention
B. Publications
- Rennert G., Saltz-Rennert H., Wanderman K., Weitzman S. Size of acute myocardial infarcts in patients with Diabetes Mellitus. Am J Cardiol 1985;55:1629-1630.
- Strogatz DS., Siscovick DS., Weiss NS., Rennert G. Wife's Level of Education and Husband's Risk of Primary Cardiac Arrest. Am J Public Health 1988;78:1491-1493.
- Rennert G., Tamir A., Epstein L. Lung Cancer in Israel, 1962-1982. I. Jews and Arabs. Eur J Epidemiol 1988;4:461-469.
- Spencer T., Rennert G., Schade E., Shalom J. Early Detection of Breast Cancer: Compromise Guidelines for a Primary Care Setting. J Cancer Educ 1989;4:121-123.
- Siscovick DS., Strogatz DS., Weiss NS., Rennert G. Early Retirement and Risk of Primary Cardiac Arrest. Am J Publ Health 1990;80:207-208.
- Rennert G., Rennert HS., Katz L., Epstein L. Lung Cancer in Israel, 1962-1982. II. Ethnic Differences Among Jews. Eur J Epidemiol 1990:6;142-149.
- Rennert G., Epstein L. Urban-Rural Differences in Lung Cancer Occurrence. Time Trends in Jews in Israel. Lung Cancer 1990;5:9-14.
- Rennert G. The Value of Mammography in Different Ethnic Groups in Israel - Cost Effectiveness Analysis Using CAN*TROL. Cancer Detect Prev 1991;15:477-482.
- Rennert G., Rennert HS., Epstein L. Is There a Time Trend in the Smoking-Lung Cancer Histology Relationship? Cancer Detect Prev 1991;15:99-101.
- Rennert G. Teaching Preventive Oncology to Primary Care Physicians - Pretest Assessment of Knowledge in Northern Israel. Family Practice 1991;8:19-22.
- Rennert G., Rennert HS., Epstein L. Lung Cancer Histology in Jews and Arabs, Israel 1962-1982. Am Rev Resp Dis 1991;143:721-726.
- Ostbye T., Bojan F., Rennert G., Hurlen P., Garner B. Establishing an International Computer Network for Research and Teaching in Public Health and Epidemiology. Eur J Epidemiol 1991;7:34-38.
- Rennert G., Rennert HS., Epstein L. Lung Cancer Histology in Major Ethnic Groups Among the Jews. Israel, 1962-1982. Eur J Epidemiol 1991;7:68-76.
- Stein M., Lachter J., Rennert G., Bartal A., Kuten A. Thyroid Cancer and Multiple Primary Malignancies in Israel (1960-1976). J Surg Oncol 1991;47:221-224.
- Robinson E., Neugut AI., Murray T., Rennert G. A Comparison of the Clinical Characteristics of First and Second Primary Head and Neck Cancers: A Population-Based Study. Cancer 1991;68:189-192.
- Rennert G. Considerations and Parameters in Planning a National Cancer Control Program - The Implications of the Case of Israel. Publ Health Rev 1991;18:117-128.
- Rennert G. Premature Mortality, Israel, 1986. Isr J Med Sci 1992;28:81-85.
- Robinson E., Nasrallah S., Adler Z., Rennert G., Neugut AI. The Clinical, Demographic and Follow-up Characteristics of Patients with Two Primary Metachronous Tumors (one of the Tumors in the Colon). Dis Colon Rectum 1992;35:457-461.
- Robinson E., Bar-Daroma R., Rennert G., Neugut AI. A Comparison of the Clinical Characteristics of Second Primary and Single Primary Sarcoma - A Population Based Study. J Surg Oncol 1992;50:263-266.
- Stein M., Loberant N., Laviov M., Rennert G., Lachter J., Kuten A.
Second Cancer in Patients Treated for Testicular Seminoma. J Surg Oncol 1992;49:16-19.
- Robinson E., Rennert G., Rennert HS., Neugut AI. Survival of First and Second Primary Breast Cancer. Cancer 1993;71:172-176.
- Robinson E., Rennert G., Bar-Daroma R., Dori DL., Neugut AI.
The Pattern of Diagnosis of a Second Primary Tumor in the Breast. Breast Cancer Research and Treatment 1993;25:211-215.
- Bornstein J., Ben David Y., Pascal B., Zakai R., Rennert G., Hornstein L., Abramovici H. Occult Human Papillomavirus Cervical Infection: Reverse DNA Hybridization Detection and Review of the Literature. Isr J Obstet Gynecol 1993;2:58-65.
- Bornstein J., Ben-David Y., Horenstein L., Rennert G., Pascal B., Faktor J., Werhow M., Bekerman A., Zakai R., Abramovici H.
Human Papillomavirus DNA in Jewish Israeli Women. The CERVIX and the lower female genital tract 1993;1:147-152.
- Roguin A., Weyl Ben-Arush M., Rennert G., Rosenthal J.
Malignant Solid Tumors in the First Year of Life. Harefuah 1994;126:574-576.
- Rennert G. Implications of the Russian Immigration on Mortality Patterns in Israel. Int. J. Epidemiol 1994;23:751-756.
- Robinson E., Adler Z., Nasrallah S., Rennert G., Neugut AI.
Clinical characteristics of second primary tumors following breast cancer. Isr J Med Sci 1995;31:169-171.
- Robinson E., Bar-Deroma R., Epelbaum R., Rennert G., Neugut AI. The clinical characterisitcs of maligant Non-Hodgkin's Lymphoma as a second primary tumor: A population-based survey. Lymphoma & Leukemia 1995;20:297-301.
- Rennert G., Robinson E., Rennert HS., Neugut AI. Clinical characteristics of metachronous colorectal tumors. Int J Cancer 1995; 60: 743-747.
- Robinson E., Adler Z., Nasrallah S., Kuten A., Steiner M., Rennert G., Neugut AI. Clinical characteristics of patients with a second primary tumor in the endometrium or ovary. Eur. J. Gynaec. Oncol. 1995;3:195-198.
- Ge X., Yannai S., Rennert G., Gruener N., Fares FA. 3, 3' -diindolylmethane induces apoptosis in human cancer cells. Biochemical and Biophysical Reserach Communications 1996;228:153-158.
- Reshef R., Libner E., Rennert HS., Cohen I., Shiler M., Shkolnik T., Rennert G. A community hospital experience with colonoscopic Polypectomies. Isr J Med Sci 1997;33:666-673.
- Ore L., Hagoel L., Shifroni G., Rennert G. Compliance with Mammography screening in Israeli women: The impact of a pre-scheduled invitation and of letter type. Isr J. Med Sci 1997;33:103-111.
- Weinberg HS., Nevo E., Korol A., Fahima T., Shapiro S., Rennert G. Molecular changes in the offspring of liquidators from the Chernobyl disaster area in Israel. Environmental Health Perspectives 1997; 105(supp 6): 1479-1481.
- Slater PE., Lubin E., Rennert G. Screening for thyroid abnormalities among immigrants to Israel from the former USSR. Public Health Reviews 1997; 25:43-47.
- Prokocimer M., Unger R., Rennert HS., Rotter V., Rennert G.
Pooled-analysis of p53 Mutations in Hematological Malignancies Human Mutation 1998; 12:4-18.
- Fares A.F., Ge X., Yannai S., Rennert G. Dietary Indole Derivatives Induce Apoptosis in Human Breast Cancer Cells. Adv Exp Med Biol 1998; 451:153-157.
- Hagoel L., Ore L., Neter E., Shifroni G., Rennert G. The Gradient in Mammography Screening Behavior – a Lifestyle Marker. Social Science & Medicine, 1999; 48:1281-1290.
- Weinberg HSH, Korol A, Nevo E, Shapiro S, Rennert G. Increased mutation rate in offspring of the Chernobyl accident liquidators. Int J Radiation Med 1999;2:67-70.
- Yakirevich E., Ben Itzhak O., Rennert G., Kovacs ZG., Resnick MB. Cytotoxic Phenotype of Tumor Infiltrating Lymphocytes in Medullary Carcinoma of the Breast. Modern Pathology 1999; 12:1050-1056.
- Ballard-Barbash R., Klabunde C., Paci E., Broeders M., Coleman EA., Fracheboud J., Bouchard F., Rennert G., Shapiro S. Breast Cancer Screening in 22 countries: Delivery of services, notification of results, and outcomes ascertainment. Eur J Cancer Prevention 1999;8:417-426.
- Rennert G., Kitzes R., Rennert HS. Epidemiology of Candidemia - A Nationwide Survey in Israel. Infection, 2000; 28: 26-29.
- Lev Z., Kislitsin D., Rennert G., Lerner A. Utilization of K-ras Mutations Identified in Stool DNA for the Early Detection of Colorectal Cancer. J Cell Biochem 2000; Suppl 34: 35-39.
- Brenner D., Rennert G., Guest editors. Translational chemoprevention: Breast and colon cancer. Foreword. J Cell Biochem 2000; Suppl 34: v-viii.
- Yakirevich E, Maroun L, Cohen O, Ben Izhak O, Rennert G., Resnick MB. Apoptosis, proliferation, and Fas(APO-I, CD95)/Fas ligand expression in medullary carcinoma of the breast. J Pathol 2000;192:166-173.
- Hagoel L., Dishon S., Almog R., Silman Z., Rennert G. Proband family adherence to familial-genetic counseling. Psycho-Oncology 2000; 9:522-527.
- Dunning AM., Durocher F., Healey CS., McBridel SE., Carlomango F., Xu CF., Dawson E., Teare DM., Rhodes S., Uedal S., Lai E., Luben RN., Van Rensberg L., Mannermaa A., Kataja V., Rennert G., Dunham I., Bentley D., Purvis I., Easton D., Ponder BAJ. The extent of linkage disequilibrium in four populations with distinct demographic histories. Am J Human Genetics 2000;67:1544-54
- Klabunde C., Bouchard F., Taplin S., Scharpantgen A., Ballard-Barbash R., for the International Breast Cancer Screening Network (IBSN). Quality assurance for screening mammography: an international comparison. J Epidemiol Community Health 2001;55:204-12
- Rozen G.S., Rennert G., Rennert HS., Diab G., Daud D., Ish Shalom S. Calcium Intake and Bone Mass Development Among Israeli
Adolescent Girls. J Am Coll Nutr 2001;20:219-224
- Rennert G., Peterburg Y. Prevalence of Chronic Diseases in Israel. Israel Med Assoc J - IMAJ 2001;3:404-8.
- Weinberg H.S., Korol A B., Kirzhner V.M., Nevo E., Shapiro S., Rennert G., Piatak O., Stepanova E.I., Skvarskaja E. Very High Mutation Rate in Offspring of the Chernobyl Accident Liquidators.
Proc R Soc Lon B 2001;268:1001-1005
- Ore L., Hagoel L., Lavi I., Rennert G. Screening with Fecal Occult Blood Test (FOBT) for Colorectal Cancer: Assessment of Two Modes Attempting to Achieve Adherence. Eur J Cancer Prevention 2001;10:251-6
- Giordano TJ., Shedden KA., Schwartz DR., Kuick R., Taylor JMG., Lee N., Misek DE., Greenson JK., Kardia SLR., Beer DG., Rennert G., Cho KR., Gruber SB, Fearon ER, Hanash S. Organ-Specific Molecular Classification of Primary Lung, Colon and Ovarian Adenocarcinomas Using Gene Expression Profiles.
Am J Pathol 2001;159:1231-1238.
- Rennert G., Rennert HS., Miron E., Peterburg Y. Population colorectal cancer screening with fecal occult blood test. Cancer Epidemiology, Biomarkers and Prevention 2001;10:1165-1168
- Hagoel L., Ore L., Neter E., Silman Z., Rennert G. Clustering Women's Health Behaviors. Health Education & Behavior 2002; 29:170-182.
- Rennert G., Luz N., Tamir A., Peterburg Y. Chronic Disease Prevalence in Immigrants to Israel from the former USSR. J Immig Health 2002;4:29-33
- Kislitsin D., Lerner A., Rennert G., Lev Z. K-ras mutations in sporadic colorectal tumors in Israel: Unusual high frequency of codon 13 mutations and an evidence for a non-homogenous representation of mutation subtypes. Digest Dis Sci 2002;47:1073-9
- Davidson S., Leshanski L., Rennert G., Eidelman S., Amikam D.
Maternal mosaicism for a second mutational event - a novel deletion in a familial adenomatous polyposis family harboring a new germ-line mutation in the alternatively spliced-exon 9 region of APC. Human mutation 2002;19:83-4.
- Narod SA, Dub MP ,Klijn J, Lubinski J, Lynch HT, Ghadirian P, Provencherb D, Heimdahl K, Moller P, Isaacs C, Weber B, Friedman E, Gershoni-Baruch R, Rennert G, Pasini B, Wagner T, Daly M, Garber JE, Neuhausen S, Robson M, Ainsworth P, Olsson H, Gareth Evans, Osborne M, Couch F, Foulkes W, Warner E, Kim-Sing C, Olopade O, Tung N, Saal H, Weitzel J, Merajver S, Stoppa-Lyonnet D, Jernstrom H, Sun P, Brunet JS.
Oral contraceptives and the risk of breast cancer in BRCA1 and
BRCA2 carriers. J Natl Cancer Inst 2002;94:1773-9.
- Rennert G. Dietary intervention studies and cancer prevention.
European J of Cancer Prevention 2002;11:419-425.
- Rennert H., Bercovich D., Hubert A., Abeliovich D., Bar Shira A., Soloviov S., Rozovsky U., Shreiber L., Matzkin H., Rennert G., Kadouri L., Peretz T., Yaron Y., Orr-Urtreger A. A novel founder mutation in the RNASEL gene, 471delAAAG, is associated with prostate cancer in Ashkenazi Jews. Am J Hum Genet 2002;71:981-4
- Gruber SB., Ellis NA, ,Rennert G. (Corresponding Author), Offit K.
BLM heterozygosity and the risk of colorectal cancer. Science 2002;
297: 2013
- Foulkes WD, Thiffault I, Gruber SB, Horwitz M, Shia J, Markowitz A, Figer A, Friedman E, Hamel N, Farber D, Greenwood CM, Walsh T, Marcus V, Tomsho L, Gebert J, Bressac-de Paillerets B, Weitzel J, Gordon PH, MacNamara E, King MC, Hampel H, de la Chapelle A, Boyd J, Offit K, Rennert G, Chong G, Ellis NA. The founder mutation MSH2*1906G>C is an important cause of Hereditary Non Polyposis Colorectal Cancer in the Ashkenazi Jewish population. Am J Hum Genetics Dec 2002 ;71:1395-1412.
- Teare MD, Dunning AM, Durocher F, Rennert G, Easton DF
Sampling distribution of summary linkage disequilibrium measures.
Ann Hum Genet. 2002 May;66(Pt 3):223-33.
- Rennert G. Fecal Occult Blood (FOB) Screening – Trial evidence, Practice and Beyond. Recent Results in Cancer Research. Tumor Prevention and Genetics 2003;163:248-253.
- Rennert G. Political Interpretation of Scientific Evidence – Case study of breast cancer screening policies around the world. Recent Results in Cancer Research. Tumor Prevention and Genetics 2003;163: 140-150.
- Greenson JK, Bonner JD, Ben-Yzhak O, Cohen HI, Miselevich I, Resnick MB, Trougouboff P, Tomsho LD, Kim E, Low M, Rennert G, Gruber SB. Phenotype of Microsatellite Unstable Colorectal Carcinomas: Well-differentiated and focally mucinous tumors and the absence of dirty necrosis correlate with microsatellite instability. Am J Surg Pathol 2003; 27:563-70
- Rennert G. Diet and Cancer. Where are we? Where are we going? Proceedings of the Nutrition Society 2003;62:59-62.
- Rozen GS., Dodiuk RP., Rennert G., Rennert HS., Diab G., Ish-Shalom S. Calcium supplementation provides a larger window of opportunities for bone mass accretion after menarche. Am J Clin Nutr. 2003;78:993-8
- Giusti RM, Rutter JL, Duray PH, Freedman LS, Konichezky M, Fisher-Fischbein J, Greene MH, Maslansky B, Fischbein A, Gruber SB, Rennert G, Ronchetti RD, Hewitt SM, Struewing JP, Iscovich J. A Two-Fold Increase in BRCA Mutation-Related Prostate Cancer Among Ashkenazi Israelis is Not Associated with Distinctive Histopathology. J Med Genet 2003;40:787-792.
- Shedden KA., Taylor JMG., Giordano TJ., Kuick R., Misek DE., Rennert G., Schwartz DR., Gruber SB., Logsdon C., Simeone D., Kardia SLR., Greenson JK., Cho KR., Beer DG., Fearon ER., Hanash S. Accurate Molecular Classification of Human Cancers Based on Gene Expression Using a Simple Classifier With a Pathologic Tree-Based Framework. Am J Pathol. 2003;163:1985-95
- Julian-Reynier C, Welkenhuysen M, Hagoel L, Decruyenaere M, Hopwood P, on behalf of the CRISCOM* Working Group. Risk communication strategies: state of the art and effectiveness in the context of cancer genetic services. Eur J Human Genetics 2003;11:725-736.
- Niell BL, Long JC, Rennert G, Gruber SB. Genetic anthropology of the colorectal cancer susceptibility allele APC I1307K. Am J Human Genetics 2003; 73:1250-1260.
- P Hopwood, C van Asperen, E Legius F Eisinger , H Sobol, B Schelberger, G Rennert , GDR Evans, G Evers-Kieboom, M Decruyenaere, M Welkenhuysen, I Nippert, L Hoegal , G Borreani, L Gangeri, A Tibben, C Julian-Reynier. Cancer Genetics Service Provision: A Comparison of 7 European Centres. Community Genetics 2003;6:192-205
- Hagoel L, Neter E, Dishon S, Barnett O, Rennert G. BRCA1/2 Mutation carriers: living with susceptibility. Community Genetics 2003;6:242-8
- Niell BL., Rennert G., Bonner JD., Tomsho L., Gruber SB. BRCA1 and BRCA2 founder mutations and the risk of colorectal cancer. JNCI 2004;96:15-21
- Atzmon G, Schechter C, Greiner W, Davidson D, Rennert G, Barzilai N. Clinical Phenotype of Families with Longevity. J Am Geriatr Soc 2004:52;274-277
- Lipkin SM, Rozek LS, Rennert G, Yang W, Peng-Chic J, Hacia J, Hunt N, Kokoris M, Fearon E, Lynch H, Collins F, Gruber SB.
Identification of Novel DNA Mismatch Repair Gene Variants and
Association with Population Based Colorectal Cancer Susceptibility.
Nature Genetics 2004; 36(7):694-9
- Lavie O, Horenriech G, Ben-Arie A, Rennert G, Cohen Y, Keider R, Sagi S, Levy Lahad E, Auslander R, Beller U. BRCA Germline Mutations in Women with Uterine Serous Papillary Carcinoma.
Gynecologic Oncology 2004;92:521-4
- Bar-Joseph N., Reisfeld D., Tirosh E., Stoler Z., Rennert G. Neuro-behavioral cognitive performances of children exposed to low dose radiation in the Chernobyl accident. Am J Epidemiol 2004;160:453-9
- Yankaskas BC, Klabunde CN, Ancelle-Park R, Rennert G, Wang H, Fracheboud J, Pou G, Bulliard JL for the International Breast Cancer Screening Network. International comparison of recall rates for screening mammography. Can it be done? J Med Screen 2004;11:187-193
- Rennert G., Dishon S., Rennert HS, Fares F. Phenotypic characteristics of families with BRCA1 and BRCA2 mutations
in Israel. Eur J Cancer Prevention 2005; 14:357-61
- Poynter JN, Gruber SB, Higgins PDR, Almog R, Bonner JD, Rennert HS, Low M, Greenson JK, Rennert G. Statins and the Risk of Colorectal Cancer. New England Journal of Medicine 2005;352:2184-92.
- Shin B., Chen H, Rozek LS, Paxton L, Peel DJ, Anton-Culver H, Rennert G, Mutch DG, Goodfellow PJ, Gruber SB, Lipkin SM.
Low Allele Frequency of MLH1 D132H in American Colorectal and
Endometrial Cancer Patients. Dis Colon Rectum 2005;48(9):1723-7
- Rozek L.S., Lipkin SM, Fearon ER, Hanash S., Giordano TJ., Kuick R., Misek DE., Taylor JMG., Rennert G., Gruber S.B. CDX2 Polymorphisms, RNA Expression, and Risk of colorectal cancer.
Cancer Research 2005;65:5488-92
- Dodiuk-Gad RP, Rozen GS, Rennert G, Rennert HS, Ish-Shalom S. Sustained effect of short-term calcium supplementation on bone mass in adolescent girls with low calcium intake. Am J Clin Nutr. 2005;81:168-74.
- Winawer S, Faivre J, Selby J, Bertaro L, Chen TH, Kroborg O, Levin B, Mandel J, O'Morain C, Richards M, Rennert G, Russo A, Saito H, Semigfnovsky B, Wong B, Smith R. Workgroup II: the screening process. UICC International Workshop on Facilitating Screening for Colorectal Cancer, Oslo, Norway. Ann Oncol. 2005;16:31-3.
- Rennert G., Dishon S., Tomsho LP., Almog R., Low M., Bonner JD., Rennert HS., Gruber SB. Prevalence of adenomas in carriers of the I1307k APC polymorphism. Diseases Colon Rectum 2005;48:2317-21
- Cullinane CA, Lubinski J, Neuhausen SL, Ghadirian P, Lynch HT, Isaacs C, Weber B, Moller P, Offit K, Kim-Sing C, Friedman E, Randall S, Pasini B, Ainsworth P, Gershoni-Baruch R, Foulkes WD, Klijn J, Tung N, Rennert G, Olopade O, Couch F, Wagner T, Olsson H, Sun P, Weitzel JN, Narod SA. The Effect of Pregnancy as a Risk Factor for Breast Cancer in BRCA1/BRCA2 Mutation Carriers. Int J Cancer 2005;117(6):988-91
- Brenner DE, Rennert G. Fecal DNA biomarkers for the detection of colorectal neoplasia: Attractive, but is it feasible?. J Natl Cancer Inst 2005;97:1107-1109
- Eisen A, Lubinski J, Klijn J, Moller P, Lynch HT, Offit K, Weber B, Rebbeck T, Neuhausen SL, Ghadirian P, Foulkes WD, Gershoni-Baruch R, Friedman E, Rennert G, Isaacs C, Kim-Sing C, Ainsworth P, Couch F, Garber JE, Daly M, Rosen B, Olopade O, Karlan B, Tung N, Saal HM, Weitzel J, Eng C, Sun P, Narod SA.
Breast Cancer Risk Following Bilateral Oophorectomy in BRCA1 and
BRCA2 Mutation Carriers: An International Case-Control Study.
J Clin Oncol. 2005 Oct 20;23(30):7491-6.
- Poynter JN, Cooney KA, Bonner JD, Tomsho LP, Rennert G, Gruber SB. APC I1307K and the Risk of Prostate Cancer. Cancer Epidemiol Biomarker Prevent 2006;15:468-73
- Rennert G. Breast Cancer in: Freedman LS, Edwards BK, Ries LAG, Young JL, eds. Cancer Incidence in Four Member Countries of the MECC Compared with US SEER. National Cancer Institute MECC Monograph, 2006:73-81.
- Rennert G. Are we taking the right approach in planning chemoprevention studies? Nature -Clinical Practice Oncology 2006;3(9):464-5
- Orr-Urtreger A, Bar Shira A, Bercovich D, Matarasso N, Rozovsky U, Rosner S, Soloviov S, Rennert G, Hubert A, Rennert H, Matzkin H. RNASEL mutation screening and association study in Ashkenazi and non-Ashkenazi prostate cancer patients. Cancer Epidemiol Biomarker Prevent 2006;15:474-9
- Friedman E, Kotsopoulos J, Lubinski J, Lynch HT, Ghadirian P, Neuhausen SL, Isaacs C, Weber B, Foulkes WD, Moller P, Rosen B, Kim-Sing C,Gershoni-Baruch R, Ainsworth P, Daly M, Tung N, Eisen A, Olopade OI, Karlan B, Saal HM, Garber JE, Rennert G, Gilchrist D, Eng C, Offit K, Osborne M, Sun P, Narod SA and the Hereditary Breast Cancer Clinical Study Group. Spontaneous and Therapeutic Abortions and the Risk of Breast Cancer Among BRCA Mutation Carriers. Breast Cancer Res. 2006;8(2):R15. Epub 2006 Mar 21
- Rozek L.S., Rennert G., Gruber S.B. E1317Q is not associated with colorectal cancer in a population-based case- control study of northern Israelis. Cancer Epidemiology, Biomarkers and Prevention 2006;15:2325-7
- Rennert G. Prevention and early detection of colorectal cancer – new horizons. Recent Results in Cancer Research - Cancer Prevention 2007;174(15):179-187
- Kotsopoulos J, Lubinski J,. Lynch HT, Klijn J, Ghadirian P, Neuhausen SL, Kim-Sing C, Foulkes WD, Moller P, Isaacs C, Domchek S, Randall S, Offit K, Tung N, Ainsworth P, Gershoni-Baruch R, Eisen A, Daly M, Olopade OI, Karlan B, Saal HM, Couch F, Pasini B, Wagner T, Friedman E, Rennert G, Eng C, Weitzel J, Sun P, Narod SA and the Hereditary Breast Cancer Clinical Study Group. Age at first birth and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers. Breast Cancer Res Treat. 2007 Jan 24; [Epub ahead of print]
- Rennert G. Cancer Prevention: from public health interventions to individual tailoring. Eur J Cancer Prevention 2007;16(3):165-6
- Rennert G., Brenner DE, Rennert HS, Lev Z. K-ras in stool from test cards improves the positive predictive value of FOBT. Cancer Letters 2007;253:258-264
- Bar-Joseph N, Rennert G, Tamir A, Ore L, Bar-Joseph G. Ethnic differences in the epidemiologic characteristics of severe trauma due to falls from height among children in Northern Israel. Israel J Med Sci 2007;9:603-606
- Chaiter Y, Rennert G, Fischler R, Rennert H.S, Rosen G, Gruber S.B, Ben Amotz A. Dietary Intake of Carotenoid Isomers in Israel. Int J Vitamin Nutrition Research 2007 Nov;77(6):398-405
- Gruber SB, Moreno V, Rozek LS, Ballinger D , Rennert HS, Bonner JD, Almog R, Low M, Greenson JK, Giordano TJ, Lejbkowicz F, Douglas JA, Levin AM, Fearon ER, Boehnke M, Rennert G. Genetic Variation in 8q24 Associated with Risk of Colorectal Cancer. Cancer Biology and Therapeutics 2007 Jul 2;6(7) 1143-7
- Pujana MA, Han JDJ, Starita LM, Stevens KN, Tewari M, Ahn JS, Rennert G, Moreno V, Kirchhoff T, Gold B, Assmann V, ElShamy WM, Rual JF, Levine D, Rozek LS, Gelman RS, Gunsalus KC, Greenberg RA, Sobhian B, Bertin N, Venkatesan K, Ayivi-Guedehoussou N, Sol? X, Hern?ndez P, L?zaro C, Nathanson KL, Weber BL, Cusick ME, Hill DE, Offit K, Livingston DM, Gruber SB, Parvin JD, Vidal M. Network modeling links breast cancer susceptibility and centrosome dysfunction. Nature Genetics 2007 Nov;39(11):1338-1349. Epub 2007 Oct 7.
- Rennert G., Bisland-Naggan S., Bar-Joseph N., Zhang S., Barnett-Griness O., Rennert HS., Narod S. Outcome of Breast Cancer in BRCA Mutation Carriers in Israel. New England Journal of Medicine 2007;357:115-23
- Antoniou AC, Sinilnikova OM, Simard J, L?on? M, Dumont M, Neuhausen SL, Struewing JP, Stoppa Lyonnet D, Barjhoux L, Hughes DJ, Coupier I, Belotti M, Lasset C, Bonadona V, Bignon YJ, GEMO, Rebbeck TR, Wagner T, Lynch HT, Domchek SM, Nathanson KL, Garber JE, Weitzel J, Narod SA, Tomlinson G, Olopade OI, Godwin A, Isaacs C, Jakubowska A, Lubinski J, Gronwald J, G?rski B, Byrski T, Huzarski T, Peock S, Cook M, Baynes C, Murray A, Rogers M, Daly PA, Dorkins H, EMBRACE, Schmutzler RK, Versmold B, Engel C, Meindl A, Arnold N, Niederacher D, Deissler H, Spurdle AB, Chen X, Waddell N, Cloonan N, kConFab, Kirchhoff T, Offit K, Friedman E, Kaufmann B, Laitman Y, Galore G, Rennert G, Lejbkowicz F, Raskin L, Irene L. Andrulis IL, Ilyushik E, Ozcelik H, Devilee P, Vreeswijk MPG, Greene MH, Prindiville SA, Osorio A, Ben?tez J, Zikan M, Szabo CI, Kilpivaara O, Nevanlina H, Hamann U, Durocher F, Arason A, Couch FJ, Easton DF and Chenevix-Trench G on behalf of the Consortium of Investigators of Modifiers of BRCA1/2. RAD51 135G>C modifies breast cancer risk among BRCA2 mutation carriers: Results from a combined analysis of 19 studies. Am J Human Genetics 2007 Dec;81(6):1186-200. Epub 2007 Oct 16.
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Kogan A., Shapira R., Tamir A., Rennert G. Antithrombotic therapy for prevention of stroke in clinical practice in the ED. Am J Emerg Med 2007;25:1-5
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Rennert G. Prevention and early detection of colorectal cancer – new horizons. Recent Results in Cancer Research - Cancer Prevention 2007;174(15):179-187
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Rennert G.
Cancer Prevention: from public health interventions to individual tailoring.
Eur J Cancer Prevention 2007;16(3):165-6
- Lavie O, Barnett O, Narod S, Rennert G. The risk of developing uterine sarcoma after tamoxifen use.
Int J Gynecol Cancer 2008;18:352-6.
- Chao EC, Velasquez JL, Witherspoon MS, Rozek LS, Peel D, Ng P, Gruber SB, Watson P, Rennert G, Anton-Culver H, Lynch H, Lipkin SM. Accurate classification of MLH1/MSH2 missense variants with multivariate analysis of protein polymorphisms-mismatch repair (MAPP-MMR).
Hum Mutat. 2008; 29(6):852-60.
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Lavie O, Gruber SB, Leibkowicz F, Dishon S, Rennert G. Gynecological malignancies in Ashkenazi families with the MSH2 A636P founder mutation.
Am J Obstet Gynecol 2008 Aug;199(2):148.e1-3
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Almog R, Hagoel L, Tamir A, Barnett O, Rennert G. Quality Control in a National Program for the Early Detection of Breast Cancer Women's Satisfaction With the Mammography Process. Women's Health Issues 2008;18:110-7.
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Antoniou AC Antoniou AC, Spurdle AB, Sinilnikova OM, Healey S, Pooley KA, Schmutzler RK, Versmold B, Engel C, Meindl A, Arnold N, Hofmann W, Sutter C, Niederacher D, Deissler H, Caldes T, K?mpj?rvi K, Nevanlinna H, Simard J, Beesley J, Chen X; the Kathleen Cuningham Consortium for Research into Familial Breast Cancer, Neuhausen SL, Rebbeck TR, Wagner T, Lynch HT, Isaacs C, Weitzel J, Ganz PA, Daly MB, Tomlinson G, Olopade OI, Blum JL, Couch FJ, Peterlongo P, Manoukian S, Barile M, Radice P, Szabo CI, Pereira LH, Greene MH, Rennert G, Lejbkowicz F, Barnett-Griness O, Andrulis IL, Ozcelik H; OCGN, Gerdes AM, Caligo MA, Laitman Y, Kaufman B, Milgrom R, Friedman E; The Swedish BRCA1 and BRCA2 study collaborators, Domchek SM, Nathanson KL, Osorio A, Llort G, Milne RL, Ben?tez J, Hamann U, Hogervorst FB, Manders P, Ligtenberg MJ, van den Ouweland AM; The DNA-HEBON collaborators, Peock S, Cook M, Platte R, Evans DG, Eeles R, Pichert G, Chu C, Eccles D, Davidson R, Douglas F; EMBRACE, Godwin AK, Barjhoux L, Mazoyer S, Sobol H, Bourdon V, Eisinger F, Chompret A, Capoulade C, Bressac-de Paillerets B, Lenoir GM, Gauthier-Villars M, Houdayer C, Stoppa-Lyonnet D; GEMO, Chenevix-Trench G, Easton DF; on behalf of CIMBA.on behalf of CIMBA. Common breast cancer predisposition alleles are associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers. Am J Human Genet 2008 ;82(4):937-48.
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Tenesa A, Farrington SM, Prendergast JG, Porteous ME, Walker M, Haq N, Barnetson RA, Theodoratou E, Cetnarskyj R, Cartwright N, Semple C, Clark AJ, Reid FJ, Smith LA, Kavoussanakis K, Koessler T, Pharoah PD, Buch S, Schafmayer C, Tepel J, Schreiber S, V?lzke H, Schmidt CO, Hampe J, Chang-Claude J, Hoffmeister M, Brenner H, Wilkening S, Canzian F, Capella G, Moreno V, Deary IJ, Starr JM, Tomlinson IP, Kemp Z, Carvajal-Carmona L, Webb E, Broderick P, Vijayakrishnan J, Houlston RS, Rennert G, Ballinger D, Rozek L, Gruber SB, Matsuda K, Kidokoro T, Nakamura Y, Zanke BW, Greenwood CM, Rangrej J, Kustra R, Montpetit A, Hudson TJ, Gallinger S, Campbell H, Dunlop MG. Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21. Nature Genetics 2008 ;40(5):631-7
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Raskin L, Pinchev M, Arad C, Lejbkowicz F, Tamir A, Rennert HS, Rennert G, Gruber SB. FGFR2 Is a Breast Cancer Susceptibility Gene in Jewish and Arab Israeli Populations. Cancer Epidemiol Biomarkers Prev 2008;17 1060-1065.
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Yizhaki D., Rennert H.S., Rosen G., Rennert G. Validity and Reproducibility of a Semi-quantitative Food Frequency Questionnaire adapted to an Israeli Population.
The Open Nutrition Journal 2008;2:9-14.
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Samiran S, Gruber SB, Mukherjee B, Rennert G. Inference of Haplotype Effect in Matched Case-Control Study Using unphased Genotype Data. International Journal of Biostatistics 2008 ;4(1):6
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Greenson JK, Huang SC , Herron C, Bonner JD, Tomsho LD, Kim E, Ben Yizhak O, Cohen HI, Trougouboff P, Bejhar J, Sova Y, Pinchev M, Rennert G, Gruber SB.
Pathologic Predictors of Microsatellite Instability in Colorectal Cancer. Am J Surg Pathol 2008 Sep 30. [Epub ahead of print] 2009;33:126-133.
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Mukherjee B, Ahn J, Gruber SB, Rennert G, Moreno V, Chatterjee N.
Tests for gene-environment interaction from case-control data: a novel study of type I error, power and designs. Genet Epidemiol. 2008 Nov;32(7):615-26.
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Almog R, Ezra G, Lavi I, Rennert G, Hagoel L. The Public Prefers Fecal Occult Blood Test (FOBT) over Colonoscopy for Colorectal Cancer (CRC) Screening.
Eur J Cancer Prevention 2008 Oct;17(5):430-7
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Eisen A, Lubinski J, Gronwald J, Moller P, Lynch HT, Klijn J, Kim-Sing C, Neuhausen SL, Gilbert L, Ghadirian P, Manoukian S, Rennert G, Friedman E, Isaacs C, Rosen E, Rosen B, Daly M, Sun P, Narod SA; the Hereditary Breast Cancer Clinical Study Group. Hormone Therapy and the Risk of Breast Cancer in BRCA1 Mutation Carriers.
J Natl Cancer Inst. 2008 Oct 1;100(19):1361-7. Epub 2008 Sep 23.
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Khoury Shakour S., Leijbcovich F, Raskin L, Barnett-Griness O., Rennert H, Gruber S, Rennert G. Recreational physical activity modifies the association between the common GH1 Polymorphism and colorectal cancer risk. Cancer Epidemiol Biomarker Prev 2008 Dec;17(12):3314-8.
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Toland AE, Rozek LS, Presswala S, Rennert G, Gruber SB. PTPRJ Haplotypes and Colorectal Cancer Risk. Cancer Epidemiol Biomarkers Prev. 2008 Oct;17(10):2782-5.
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Neter, E., Almog, R., Ore, L., Rennert, G., Hagoel, L. The Israeli National Program for Early Detection of Breast Cancer: Women as the Target Population. Cognition, Brain, Behavior 2009;13:195-205.
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Raskin L., Rennert G., Gruber SB. FOXP3 germline polymorphisms are not associated with risk of breast cancer. Cancer Genetics Cytogenetics 2009;190:40-2.
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Taddei TH, Kacena KA, Yang M, Yang R, Malhotra A , Sadan S, Boxer M, Aleck KA, Rennert G, Mistry PK. The under-recognized progressive nature of N370S Gaucher Disease and assessment of cancer risk in 403 patients. Am J Hematol 2009 Apr;84(4):208-14. Jan 12 (E-Pub)
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Raskin L, Lejbkowicz F, Barnett-Griness O, Dishon S, Almog R, Rennert G. BRCA1 Breast Cancer Risk Is Modified by CYP19 Polymorphisms in Ashkenazi Jews. Cancer Epidemiol Biomarkers Prev. 2009 May;18(5):1617-23. Apr 14. [Epub ahead of print]
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Vilar E, Mukherjee B, Kuick R, Raskin L, Misek DE, Taylor JM, Giordano TJ, Hanash SM, Fearon ER, Rennert G, Gruber SB. Gene Expression Patterns in Mismatch Repair-Deficient Colorectal Cancers Highlight the Potential Therapeutic Role of Inhibitors of the Phosphatidylinositol 3-Kinase-AKT-Mammalian Target of Rapamycin Pathway. Clin Cancer Res. 2009 Apr 15;15(8):2829-39. Epub 2009 Apr 7.
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Khoury-Shakour S, Lejbkowicz F, Barnett-Griness O, Tamir A, Pinchev M, Rennert G. Genetic variation in IGF-1 and breast cancer risk in Ashkenazi carriers and noncarriers of BRCA1/2 mutations. Eur J Cancer Prev. 2009 Sep;18(5):361-7
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Chaiter Y, Gruber SB, Ben-Amotz A, Almog R, Rennert HS, Fischler R, Rozen G, Rennert G. Smoking attenuates the negative association between carotenoids consumption and colorectal cancer risk. Cancer Causes Control. 2009 Jun 27. [Epub ahead of print]
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Antoniou AC, Sinilnikova OM, McGuffog L, Healey S, Nevanlinna H, Heikkinen T, Simard J, Spurdle AB, Beesley J, Chen X; The Kathleen Cuningham Foundation Consortium for Research into Familial Breast Cancer, Neuhausen SL, Ding YC, Couch FJ, Wang X, Fredericksen Z, Peterlongo P, Peissel B, Bonanni B, Viel A, Bernard L, Radice P, Szabo CI, Foretova L, Zikan M, Claes K, Greene MH, Mai PL, Rennert G, Lejbkowicz F, Andrulis IL, Ozcelik H, Glendon G; OCGN, Gerdes AM, Thomassen M, Sunde L, Caligo MA, Laitman Y, Kontorovich T, Cohen S, Kaufman B, Dagan E, Baruch RG, Friedman E, Harbst K, Barbany-Bustinza G, Rantala J, Ehrencrona H, Karlsson P, Domchek SM, Nathanson KL, Osorio A, Blanco I, Lasa A, Ben?tez J, Hamann U, Hogervorst FB, Rookus MA, Collee JM, Devilee P, Ligtenberg MJ, van der Luijt RB, Aalfs CM, Waisfisz Q, Wijnen J, van Roozendaal CE; HEBON, Peock S, Cook M, Frost D, Oliver C, Platte R, Evans DG, Lalloo F, Eeles R, Izatt L, Davidson R, Chu C, Eccles D, Cole T, Hodgson S; EMBRACE, Godwin AK, Stoppa-Lyonnet D, Buecher B, L?on? M, Bressac-de Paillerets B, Remenieras A, Caron O, Lenoir GM, Sevenet N, Longy M, Ferrer SF, Prieur F; GEMO, Goldgar D, Miron A, John EM, Buys SS, Daly MB, Hopper JL, Terry MB, Yassin Y; Breast Cancer Family Registry, Singer CF, Gschwantler-Kaulich D, Staudigl C, Hansen TV, Barkardottir RB, Kirchhoff T, Pal P, Kosarin K, Offit K, Piedmonte M, Rodriguez GC, Wakeley K, Boggess JF, Basil J, Schwartz PE, Blank SV, Toland AE, Montagna M, Casella C, Imyanitov EN, Allavena A, Schmutzler RK, Versmold B, Engel C, Meindl A, Ditsch N, Arnold N, Niederacher D, Dei?ler H, Fiebig B, Suttner C, Sch?nbuchner I, Gadzicki D, Caldes T, de la Hoya M, Pooley KA, Easton DF; Georgia Chenevix-Trench; on behalf of CIMBA. Common variants in LSP1, 2q35 and 8q24 and breast cancer risk for BRCA1 and BRCA2 mutation carriers. Hum Mol Genet. 2009 Aug 5. [Epub ahead of print]
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Rennert G, Rennert HS, Pinchev M, Lavi O, Gruber SB. The use of HRT and the risk of colorectal cancer. J Clin Oncol 2009 Aug 24. [Epub ahead of print].
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Sinilnikova OM, Antoniou AC, Simard J, Healey S, L?on? M, Sinnett D, Spurdle AB, Beesley J, Chen X; kConFab8, Greene MH, Loud JT, Lejbkowicz F, Rennert G, Dishon S, Andrulis IL; OCGN11, Domchek SM, Nathanson KL, Manoukian S, Radice P, Konstantopoulou I, Blanco I, Laborde AL, Dur?n M, Osorio A, Benitez J, Hamann U, Hogervorst FB, van Os TA, Gille HJ; HEBON23, Peock S, Cook M, Luccarini C, Evans DG, Lalloo F, Eeles R, Pichert G, Davidson R, Cole T, Cook J, Paterson J, Brewer C; EMBRACE3, Hughes DJ, Coupier I, Giraud S, Coulet F, Colas C, Soubrier F, Rouleau E, Bi?che I, Lidereau R, Demange L, Nogues C, Lynch HT; GEMO1242, Schmutzler RK, Versmold B, Engel C, Meindl A, Arnold N, Sutter C, Deissler H, Schaefer D, Froster UG; GC-HBOC4344454647484950, Aittom?ki K, Nevanlinna H, McGuffog L, Easton DF, Chenevix-Trench G, Stoppa-Lyonnet D. The TP53 Arg72Pro and MDM2 309G>T polymorphisms are not associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers. Br J Cancer. 2009 Aug 25. [Epub ahead of print]
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Kogan A, Shapira R, Lewis BS, Tamir A, Rennert G. The use of exercise stress testing for the management of low-risk patients with chest pain. Am J Emerg Med 2009 Sep;27(7):889-92.
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Rennert G. Are we getting closer to molecular population screening for colorectal cancer? JNCI Journal of the National Cancer Institute 2009 June 16; doi: 10.1093/jnci/djp163
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Kershenbaum A, Lavi I, Rennert G, Almog R. Faecal occult blood screen test performance indicators in warfarin treated patients. Dis Colon Rectum 2009 (accepted)
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